Is It Possible to Unclog Your Arteries?

要把這個清除動脈的plague，這篇說是可能的，不知道是真的假的。

Eat Unsaturated fat

1. Monounsaturated fats are found in high concentrations in:

  • Olive, peanut, and canola oils
  • Avocados
  • Nuts such as almonds, hazelnuts, and pecans
  • Seeds such as pumpkin and sesame seeds

2. Polyunsaturated fats are found in high concentrations in

  • Sunflower, corn, soybean, and flaxseed oils
  • Walnuts
  • Flax seeds
  • Fish
  • Canola oil – though higher in monounsaturated fat, it’s also a good source of polyunsaturated fat.

Omega-3 fats are an important  type of polyunsaturated fat. The body can’t make these, so they must come from food.

  • An excellent way to get omega-3 fats is by eating fish 2-3 times a week.
  • Good plant sources of omega-3 fats include flax seeds, walnuts, and canola or soybean oil.

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How to lower Triglycerides

  • Normal — Less than 150 milligrams per deciliter (mg/dL), or less than 1.7 millimoles per liter (mmol/L)
  • Borderline high — 150 to 199 mg/dL (1.8 to 2.2 mmol/L)
  • High — 200 to 499 mg/dL (2.3 to 5.6 mmol/L)
  • Very high — 500 mg/dL or above (5.7 mmol/L or above)

What’s the best way to lower triglycerides?

Healthy lifestyle choices are key:

  • Exercise regularly. Aim for at least 30 minutes of physical activity on most or all days of the week. Regular exercise can lower triglycerides and boost “good” cholesterol. Try to incorporate more physical activity into your daily tasks — for example, climb the stairs at work or take a walk during breaks.
  • Avoid sugar and refined carbohydrates. Simple carbohydrates, such as sugar and foods made with white flour or fructose, can increase triglycerides.
  • Lose weight. If you have mild to moderate hypertriglyceridemia, focus on cutting calories. Extra calories are converted to triglycerides and stored as fat. Reducing your calories will reduce triglycerides.
  • Choose healthier fats. Trade saturated fat found in meats for healthier fat found in plants, such as olive and canola oils. Instead of red meat, try fish high in omega-3 fatty acids — such as mackerel or salmon. Avoid trans fats or foods with hydrogenated oils or fats.
  • Limit how much alcohol you drink. Alcohol is high in calories and sugar and has a particularly potent effect on triglycerides. If you have severe hypertriglyceridemia, avoid drinking any alcohol.

What about medication?

If healthy lifestyle changes aren’t enough to control high triglycerides, your doctor might recommend:

  • Statins. These cholesterol-lowering medications may be recommended if you also have poor cholesterol numbers or a history of blocked arteries or diabetes. Examples of statins include atorvastatin calcium (Lipitor) and rosuvastatin calcium (Crestor).
  • Fibrates. Fibrate medications, such as fenofibrate (TriCor, Fenoglide, others) and gemfibrozil (Lopid), can lower your triglyceride levels. Fibrates aren’t used if you have severe kidney or liver disease.
  • Fish oil. Also known as omega-3 fatty acids, fish oil can help lower your triglycerides. Prescription fish oil preparations, such as Lovaza, contain more-active fatty acids than many nonprescription supplements. Fish oil taken at high levels can interfere with blood clotting, so talk to your doctor before taking any supplements.
  • Niacin. Niacin, sometimes called nicotinic acid, can lower your triglycerides and low-density lipoprotein (LDL) cholesterol — the “bad” cholesterol. Talk to your doctor before taking over-the-counter niacin because it can interact with other medications and cause significant side effects.

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動脈阻塞

*我不是醫生。這只是我的個人筆記。要做任何改變，先問問你的醫師。

拖了一年，終於去看心臟科醫師，他要我做CT Calcium Score。做了，結果是心臟動脈有微度(mild)的plague，其實快要到中度，到了中度，3-5年內有心臟病的風險。

心臟病？從來也沒想過這會發生在我身上。

於是去Google，有沒有可能把plague溶掉(dissolve)，當然主流的是說不可能，只能減緩。當然一定有非主流的醫生(**)說這是可以做到的, 像這一篇文章的作者。他在2015做了CMIT(Carotid Intima-Media Thickness), 發現他血管有沉積(plagues), 他的動脈像是73歲人, 而他當時年紀是57. 他說他做了以下的事，清除了血管的沉積物，一年後，再做一次CMIT, 把動脈年齡降到52.

  1. 常吃Salmon，像一個星期三次。
  2. 吃niacin, 2gm(2,000mg)
  3. 控制高血壓，他改吃ACE inhibitor (Ramipril)
  4. 吃statin. statin是降低壞膽固醇(LDL)的藥，他從5mg開始。

**我沒去查證他們是不是真的醫生。

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Prompt Engineering 2023-03-06

From this article.

zero-shot chain of thought: asking ChatGPT “What is the fourth word in the phrase ‘I am not what I am?’ ChatGPT: not. The author said a little of zero-shot chain of thought can help get the right answer.

ChatGPT does perform much better when you provide more context and specific examples.

…

In the language models developed by OpenAI, there are two primary techniques used to activate its vast store of knowledge and improve the accuracy of responses to prompts.

These techniques are known as “few-shot learning” and “fine-tuning”.

…

The oddly named “few-shot” learning, is where the model is trained to recognise and classify a new object or concept with a small number of training examples, typically less than 10, but numbers can vary. For learning where there is only one example, you might also hear it being called “one-shot” learning.

Few-shot learning in OpenAI models can be implemented at both the ChatGPT prompt, as well as programmatically by calling the OpenAI API (Application Programming Interface) “completion” endpoint.

…

The “genius in the room” mental model

Jessica recommends three best practices when constructing a prompt to extract the most relevant answers from ChatGPT, as follows:

  1. Explain the problem you want the model to solve
  2. Articulate the output you want — in what format (“ answer in a bulleted list”), in what tone/style (“answer the question as a patient math teacher…”)
  3. Provide the unique knowledge needed for the task

…

Zero-Shot Chain of Thought (CoT) Prompting

You may also hear people talking about “zero-shot” learning, where a model is able to classify new concepts or objects that it has not encountered before.

To use this technique, all you need do is to append the words:

“let’s think step by step”, or

“thinking aloud”

At the end of your prompt!

…

Fine-tuning

A minimum of a few hundred examples should be your starting point

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